Arsenal boss Unai Emery is likely to send out another strong side as Arsenal look to stamp their authority on Group F.
The Gunners despatched Frankfurt 3-0 in their Europa League opener a fortnight ago and will hope to make another big stride towards the knockout stages tonight.
Left-back Kieran Tierney seems certain to start after missing out on action during Monday’s 1-1 draw with Manchester United .
Tierney faced a delayed start to his Arsenal career after signing from Celtic this summer as he picked up a hip injury in pre-season.
Emery said of the 22-year-old Scot: “He needs time, confidence, training and playing.
“Tomorrow is a good opportunity, he is ready to play. He will take minutes and confidence.
“He will be able with us to show his progress. I asked Kieran yesterday because we were waiting first for him to be with us consistently. Each step yesterday is important to be consistent.
“He didn’t play in Manchester because he had a small problem, not important, but the doctor told us it was important for him to be here with us, preparing for tomorrow.”
Hector Bellerin could also line up in defence for Arsenal as he too continues his return from a long-term injury.
Emiliano Martinez kept an impressive clean sheet away to Frankfurt and will again deputise for Bernd Leno.
The Argentine has plans to usurp the German and again get a chance to impress Emery on a big stage.
Joe Willock is expected to start but Emile Smith Rowe is injured and misses out.
Mesut Ozil was left out against the Red Devils but Emery could bring him in to add some creativity in the middle of the pitch.
Arsenal predicted XI (4-2-1-3): Martínez; Bellerin, Mustafi, Holding, Tierney; Ceballos, Willock; Ozil; Pepe, Aubameyang, Nelson.
Standard Liege predicted XI (4-2-3-1): Milinkovic-Savic; Vojvoda, Vanheusden, Laifis, Gavory; Cimirot, Bastien; Lestienne, M’Poku, Carcela; Emond.