The Red Devils duo were both major doubts for the Premier League showdown at Old Trafford.
But both came through fitness tests at Carrington on Monday morning, before the United squad reported to the Lowry Hotel ahead of the encounter.
Now boss Ole Gunnar Solskjaer must decide whether to start the homegrown striker and World Cup winner, as they look for a third Premier League win of the campaign.
Solskjaer had declared on Friday that he “wouldn’t put my life” on Rashford being fit for Monday night’s meeting with Unai Emery’s men, having been forced off at West Ham eight days ago.
Pogba picked up an ankle injury in last week’s Carabao Cup tie with Rochdale, with swelling worrying United medical staff on Friday.
“He got a knock to his ankle, which is very swollen,” the Norwegian stated.
“So it was better for him not to go there with the team and he’s in a race for Monday. That’s just the way it is.”
But Pogba is now expected to take his place in midfield alongside Scott McTominay, while Rashford is likely to get the nod ahead of youngster Mason Greenwood to start as the attacking focal point.
And Solskjaer will be hoping his striker delivers after admitting their struggles to find the back of the net is a cause for concern: “We need to score more goals, definitely. We’re working on improving the relationships, the patterns, the understanding.
“We’ve started at one end with the foundations, I think that we’ve done great defensively but we’re not happy with the return going forward.”
United have won just two of their opening six league matches and are already 13 points behind runaway leaders Liverpool , albeit having played one less match.
Asked whether he still sees United as a top-four side, Solskjaer replied: “I think so, yeah.
“The top two last season ( Manchester City and Liverpool) were too far ahead from the rest of us. I think we should be in and around the places behind there.